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Drug Interactions

This medication may potentially interact with a number of other medications (see Drug Interactions With Fingolimod).

What If I Take an Overdose of Fingolimod?

An overdose with fingolimod can cause a dangerously low heart rate and heart rhythm problems. If you happen to overdose on this drug, seek immediate medical attention.
(Click Gilenya Overdose for more information.)

What Should I Do If I Miss a Dose?

If you forget to take your dose, take it as soon as you remember. If it is almost time for your next dose, skip the one you missed, and continue with your regular schedule. Do not take a double dose.
If you forget to take your dose for one or more days within the first two weeks of treatment, let your healthcare provider know. Your healthcare provider may want to monitor you when you start taking fingolimod again to make sure your heart rate does not drop too low.

How Does This Medication Work?

It is still unclear how exactly fingolimod works to treat MS. The drug is classified as a "sphingosine 1-phosphate receptor modulator." It binds to certain receptors in the body and prevents lymphocytes from leaving the lymph nodes. This decreases the number of lymphocytes in the bloodstream. Lymphocytes (a type of white blood cell) play an important role in the immune system.

Clinical Effects

Clinical studies have shown that fingolimod decreases the relapse rate in people with MS, compared to a placebo (a "sugar pill" that does not contain any active ingredients). Studies have also shown that fingolimod decreases new (or newly enlarged) brain lesions, as seen with magnetic resonance imaging (MRI).
Know the Signs - Concussion Safety

Fingolimod Drug Information

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