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Drug Interactions With Felbamate

More Information on Drug Interactions With Felbamate

The following sections explain in detail the potentially negative interactions that can occur when felbamate is combined with any of the drugs listed above.
 
Barbiturates
Taking felbamate with phenobarbital or other barbiturates can increase the level of the barbiturate in your blood, increasing your risk of side effects. Taking these medications together can also decrease the level of felbamate in your blood, making it less effective. Your healthcare provider may need to adjust your doses of these medications if you take them together.
 
Birth Control Pills (Oral Contraceptives)
Combining felbamate with birth control pills can make the birth control pills less effective. This may increase the chance that you will become pregnant or cause irregular menstrual cycles and bleeding between cycles. Talk to your healthcare provider about other birth control methods if you are taking felbamate.
 
Carbamazepine
Taking felbamate with carbamazepine can decrease the level of both medications in your blood, making both less effective. Your healthcare provider may need to adjust your felbamate and carbamazepine doses if you take these medications together.
 
CYP 3A4 Inducer Medications
The body breaks down felbamate using enzymes in the liver known as CYP 3A4 enzymes. Medications known as CYP 3A4 inducers can increase the activity of these enzymes. Therefore, combining felbamate with a CYP 3A4 inducer may decrease the level of felbamate in your body, making it less effective. If you are taking these medications together, your healthcare provider may need to increase your felbamate dosage.
 
CYP 3A4 Inhibitor Medications
The body breaks down felbamate using enzymes in the liver known as CYP 3A4 enzymes. Medications known as CYP 3A4 inhibitors can decrease the activity of these enzymes. Thus, combining felbamate with a CYP 3A4 inhibitor may increase the level of felbamate in your body, increasing your risk of side effects. If you are taking these medications together, your healthcare provider may need to decrease your felbamate dose.
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Felbamate Drug Information

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