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Side Effects of Ezogabine

Common Side Effects

Ezogabine has been studied extensively in clinical trials. In these studies, the side effects that occurred in a group of people taking ezogabine (plus their usual seizure medications) were documented and then compared to the side effects that occurred in another group of people taking their usual seizure medications plus a placebo (a "sugar pill" that does not contain any active ingredients). As a result, it was possible to see what side effects occurred, how often they appeared, and how they compared to the group taking the placebo.
 
Because ezogabine was used in combination with other seizure medications (not used alone) in clinical studies, the information from these studies probably does not accurately reflect the true incidence of side effects that ezogabine actually causes.
 
In these studies, the most common side effects of ezogabine (plus other seizure medications) included:
 
  • Dizziness -- in up to 32 percent of people
  • Drowsiness -- up to 27 percent
  • Fatigue -- up to 16 percent
  • Confusion -- up to 16 percent
  • Shakiness (tremors) -- up to 12 percent
  • Coordination problems -- up to 12 percent.
 
Other common side effects, occurring in 2 to 10 percent of people, included:
 
  • Double vision
  • Blurred vision
  • Nausea
  • Constipation
  • Indigestion or heartburn
  • General weakness
  • The flu
  • Weight gain
  • Memory problems
  • A spinning sensation (vertigo)
  • Trouble paying attention
  • Changes in walking gait
  • Difficulty speaking
  • Balance problems
  • Unusual sensations (such as numbness or tingling)
  • Memory loss (amnesia)
  • Anxiety
  • Disorientation
  • Psychiatric disorders (unspecified)
  • Hallucinations
  • Painful urination
  • Difficulty passing urine
  • Blood in the urine
  • Abnormal urine color.
 
Know the Signs - Concussion Safety

Ezogabine Drug Information

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