Drug Interactions With Ezogabine

Taking carbamazepine, alcohol, phenytoin, or digoxin in combination with ezogabine may cause negative drug interactions. People taking these medications may need to be carefully monitored when starting or stopping ezogabine, or when the ezogabine dosage is adjusted. Some of these reactions can increase your risk for side effects or decrease the levels of ezogabine in your blood.

An Overview of Ezogabine Interactions

Ezogabine (Potiga™) may react with a number of other medications. Some of the drugs that can lead to interactions with ezogabine include but are not limited to:
 
 

More Detail on Drug Interactions With Ezogabine

The following sections explain in detail the potentially negative reactions that can occur when ezogabine is combined with any of the drugs listed above.
 
Alcohol
Taking ezogabine with alcohol can increase the level of ezogabine in the blood. This can increase the risk for side effects.
 
Carbamazepine
Some studies suggest that carbamazepine may decrease the level of ezogabine in the blood. This should be taken into consideration when a person taking ezogabine starts or stops taking carbamazepine, or even when the carbamazepine dosage is changed.
 
Digoxin
Ezogabine may increase the level of digoxin in the blood, increasing the risk for digoxin side effects. People taking digoxin should be carefully monitored when ezogabine is stopped or started, or even when the ezogabine dosage is changed.
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Written by/reviewed by: Kristi Monson, PharmD
Last reviewed by: Kristi Monson, PharmD
 
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