Nervous System Channel
Topics
Medications
Quicklinks
Related Channels
Drug Interactions With Ethosuximide
Interested in a Discount on Ethosuximide?
Enter your email address to see if eMedTV's free DiscountRx service has a program that could help you save on your prescription(s).
Thank you!
Thank you for your interest in DiscountRx from eMedTV. An email has been sent to the address you provided. Please follow the link within that email to see what offers may be available.
The following sections explain in detail the potentially negative interactions that can occur when ethosuximide is combined with any of the drugs listed above.
Certain Antibiotics or Antifungals
Some antibiotics or antifungal medications can increase the level of ethosuximide in your blood, increasing your risk of ethosuximide side effects. Talk with your healthcare provider before combining these medications.
Certain Anticonvulsants
Some anticonvulsants can decrease the level of ethosuximide in your blood, perhaps making it less effective. In addition, ethosuximide may affect the levels of other anticonvulsants in your blood. Your healthcare provider may need to adjust your dose of these medications.
Protease Inhibitors
Protease inhibitors may increase the level of ethosuximide in your blood, increasing your risk of ethosuximide side effects. Your healthcare provider may recommend a lower ethosuximide dose if you are taking a protease inhibitor.
Valproic Acid (Depakene) or Divalproex Sodium (Depakote, Depakote ER)
Valproic acid or divalproex sodium can affect the level of ethosuximide in your blood (usually increasing the level, although it has also been reported to decrease the level). Your healthcare provider may need to adjust your ethosuximide dose.
It is possible that not all ethosuximide drug interactions were discussed in this article. Therefore, you should talk with your pharmacist or healthcare provider about any specific drug interactions with ethosuximide that may apply to you.
Written by/reviewed by: Kristi Monson, PharmD; Arthur Schoenstadt, MD
Last reviewed by: Kristi Monson, PharmD



