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Drug Interactions With Eletriptan
Some potential drug interactions with eletriptan involve medications such as some antidepressants, certain antifungals, and ergot medications. Some of these interactions can increase your risk of side effects or cause a dangerous group of symptoms known as serotonin syndrome. Therefore, be sure to talk to your healthcare provider about potential drug interactions with eletriptan that may apply to you.
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Eletriptan hydrobromide (Relpax®) can potentially interact with many medicines. Some of the medicines that may lead to eletriptan interactions include:
- Certain antibiotics or antifungals, including:
- Clarithromycin (Biaxin®)
- Erythromycin (Ery-Tab®)
- Isoniazid (Nydrazid®)
- Itraconazole (Sporanox®)
- Ketoconazole (Nizoral®)
- Miconazole
- Telithromycin (Ketek®)
- Conivaptan (Vaprisol®)
- Delavirdine (Rescriptor®)
- Diclofenac (Cataflam®, Voltaren®)
- Ergot medications, such as:
- Bromocriptine (Parlodel®)
- Dihydroergotamine (Migranal®)
- Ergotamine (Bellamine S, Cafergot®, Ergomar®)
- Pergolide (Permax®)
- Imatinib (Gleevec®)
- Nefazodone (Serzone®)
- Nicardipine (Cardene®)
- Propofol (Diprivan®)
- Protease inhibitors, such as:
- Amprenavir (Agenerase®)
- Atazanavir (Reyataz®)
- Fosamprenavir (Lexiva®)
- Indinavir (Crixivan®)
- Nelfinavir (Viracept®)
- Ritonavir (Norvir®)
- Citalopram (Celexa®)
- Desvenlafaxine (Pristiq™)
- Duloxetine (Cymbalta®)
- Fluoxetine (Prozac®, Sarafem®, Selfemra™)
- Escitalopram (Lexapro®)
- Milnacipran (Savella™)
- Paroxetine (Paxil®, Paxil CR®, Pexeva®)
- Fluvoxamine (Luvox®, Luvox CR®)
- Sertraline (Zoloft®)
- Venlafaxine (Effexor®, Effexor XR®)
- Triptans (other migraine medications similar to eletriptan), such as:
- Almotriptan (Axert®)
- Frovatriptan (Frova®)
- Naratriptan (Amerge®)
- Rizatriptan (Maxalt®)
- Sumatriptan (Alsuma™, Imitrex®, Sumavel®, Zecuity™) or sumatriptan/naproxen sodium (Treximet®)
- Zolmitriptan (Zomig®).
Written by/reviewed by: Kristi Monson, PharmD; Arthur Schoenstadt, MD
Last reviewed by: Kristi Monson, PharmD