Eldepryl Drug Interactions

There are numerous medications that can cause potentially serious side effects when they are combined with Eldepryl. Drug interactions can occur when Eldepryl is taken with certain medications, including some antidepressants, stimulants, and allergy products. Some of these interactions can cause dangerously high blood pressure, seizures, or other problems. To avoid these complications, talk to your healthcare provider about drug interactions with Eldepryl that may apply to you.

 

Eldepryl Drug Interactions: An Overview

Eldepryl® (selegiline hydrochloride) can potentially interact with many medicines. Because there are so many Eldepryl drug interactions that are extremely dangerous, it is important to check with your healthcare provider before taking any medication, including prescription and non-prescription medications. Make sure to tell all your healthcare providers (including dentists and surgeons) that you are taking Eldepryl. Some of the medicines that may lead to Eldepryl interactions include:
 

 

    • Dextromethorphan (Robitussin DM® and many others)
    • Naphazoline (various nasal and eye drops, such as Visine-A®)
    • Oxymetazoline (various nasal and eye drops, such as Afrin®)
    • Phenylephrine (Sudafed PE® and many others)
    • Propylhexedrine (Benzedrex®)
    • Pseudoephedrine (Sudafed® and many others)

 

  • Meperidine (Demerol®)
  • Methadone (Dolophine®, Methadose®)
  • Mirtazapine (Remeron®)
  • Other monoamine oxidase inhibitors (MAOIs), including:

 

 

  • Propoxyphene medications (Balacet™, Darvon®, Darvocet®)
  • "Pressor" medications, including:

 

    • Dopamine
    • Ephedrine
    • Epinephrine (Adrenalin®, EpiPen®)
    • Isometheptene (Duradrin®, Midrin®, Migquin®, Migratine®, Migrazone®, Migrin-A®)
    • Levonordefrin (Carbocaine with Neo-Cobefrin®)
    • Midodrine (Orvaten®, ProAmatine®)
    • Norepinephrine (Levophed®)

 

 

 

  • Stimulants, such as:

 

 

 

 

(Eldepryl Drug Interactions Continued: Page 2)
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Written by/reviewed by: Kristi Monson, PharmD; Arthur Schoenstadt, MD
Last reviewed by: Kristi Monson, PharmD;