Divalproex ER Dosing (Cont.)

 
Divalproex ER Dosing for Migraines
For migraine prevention, the recommended starting dose of divalproex ER is 500 mg once daily. Your healthcare provider will probably increase your dose to 1000 mg if needed.
 

General Information on Dosing With Divalproex ER

Some considerations for people taking divalproex ER include:
 
  • Divalproex ER comes in tablet form and is taken by mouth once daily.
     
  • Divalproex ER can be taken with or without food. If the drug upsets your stomach, try taking it with food.
     
  • Do not crush, break, or chew divalproex ER tablets, as they are extended-release tablets.
     
  • Divalproex ER should be taken at the same time each day to maintain even levels of the drug in your blood.
     
  • For the medication to work properly, it must be taken as prescribed. Divalproex ER will not work if you stop taking it.
     
  • If you are unsure about anything related to your dosage or divalproex ER dosing in general, talk with your healthcare provider, nurse, or pharmacist. Do not stop taking the drug without discussing with your healthcare provider (see Depakote Withdrawal).

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Written by/reviewed by: Kristi Monson, PharmD; Arthur Schoenstadt, MD
Last reviewed by: Kristi Monson, PharmD;