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Clobazam for Seizures

A healthcare provider may recommend clobazam (Onfi™) for treating seizures associated with Lennox-Gastaut syndrome. This prescription medication is approved for use in adults and children as young as two years old, and it is only approved for use in combination with other seizure medications.
As a benzodiazepine, clobazam works by enhancing the effects of gamma-aminobutyric acid (GABA), a brain chemical that is naturally calming. GABA can slow down or stop certain nerve signals in the brain, which can help reduce the frequency of seizures.
(For a closer look at using this drug to treat seizures, click What Is Clobazam Used For?. This Web page explains what Lennox-Gastaut syndrome is and talks about possible off-label uses for clobazam.)
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