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Side Effects of Carbidopa-Levodopa-Entacapone

Common Side Effects of Carbidopa-Levodopa-Entacapone

Carbidopa-levodopa-entacapone has been studied thoroughly in clinical trials. In these studies, the side effects that occurred in a group of people taking the drug were documented and compared to side effects that occurred in another group of people taking just carbidopa-levodopa (without the entacapone). This way, it was possible to see what side effects occurred, how often they appeared, and how they compared to the group taking just carbidopa-levodopa.
In these studies, the most common side effects of carbidopa-levodopa-entacapone included:
  • Involuntary body movements (dyskinesia) -- in up to 25 percent of people
  • Nausea -- up to 14 percent
  • Diarrhea -- up to 10 percent
  • Urine discoloration -- up to 10 percent
  • Excessive muscle movements (hyperkinesia) -- up to 10 percent
  • Slow or diminished muscle movements (hypokinesia) -- up to 9 percent
  • Dizziness -- up to 8 percent
  • Abdominal pain (stomach pain) -- up to 8 percent.
Other common side effects (occurring in 1 to 6 percent of people) included:
  • Increased sweating
  • Back pain
  • Taste changes
  • Constipation
  • Vomiting
  • Dry mouth
  • Indigestion or heartburn
  • Gas
  • Red or purple bruise-like spots (known as purpura)
  • Fatigue
  • Weakness
  • Bacterial infection.

Final Thoughts on Side Effects of Carbidopa-Levodopa-Entacapone

You may experience some or none of the side effects of carbidopa-levodopa-entacapone listed in this article. Unfortunately, there is no way for your healthcare provider to know beforehand if you will have side effects from a medicine that you have never taken. Therefore, make sure to let your healthcare provider know if you develop any side effects while taking the drug or if something "just does not seem right." While it may not be a side effect of carbidopa-levodopa-entacapone, your healthcare provider will be able to diagnose and treat the problem.
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Carbidopa-Levodopa-Entacapone Info

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