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Bonine Uses

Bonine is a product that helps treat and prevent symptoms of motion sickness, such as nausea, vomiting, and dizziness. It is approved for use in both adults and children as young as 12 years old. Occasionally, healthcare providers may recommend this medication for other uses as well. "Off-label" uses of Bonine may include the treatment of nausea and vomiting due to other causes (such as morning sickness).

What Is Bonine Used For?

Bonine® (meclizine hydrochloride) is an over-the-counter motion sickness medication. In particular, it is approved to prevent and treat motion sickness symptoms (such as dizziness, nausea, and vomiting).
(This article refers to Bonine Original chewable tablets; it does not apply to Bonine for Kids, which contains a different medication.)
In general, medications for motion sickness tend to work better if they are started before symptoms begin, although some relief will usually be felt even if the medication is started after symptoms develop. Bonine is different from many other oral motion sickness and vertigo (a spinning sensation) medications in that it lasts longer and generally causes less drowsiness.
Although Bonine contains the same active ingredient as prescription meclizine (Antivert®), only prescription meclizine is approved for both motion sickness and vertigo. Bonine is not approved for treating vertigo, as this is a medical condition that requires the attention of a healthcare professional.

How Does Bonine Work?

Bonine belongs to a class of drugs called antihistamines, meaning that it blocks histamine receptors. However, it probably works for motion sickness by blocking acetylcholine receptors (by its "anticholinergic" activity). Bonine is generally not used for its antihistamine effects (such as for treating allergies).
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Bonine Drug Information

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