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Drug Interactions With Biperiden
Several medicines may cause negative drug interactions with biperiden, including tricyclic antidepressants, anticholinergics, and antipsychotic medications. These interactions can increase or decrease drug levels in your blood, which could either increase your risk for side effects or decrease the effectiveness of the medicines. If biperiden drug interactions are a concern, make sure to talk to your healthcare provider before starting any other medications.
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Biperiden hydrochloride (Akineton®) can potentially interact with several different medications. Some of the medicines that may lead to drug interactions with biperiden include:
- Acetylcholinesterase inhibitors, such as:
- Donepezil (Aricept®)
- Galantamine (Razadyne™)
- Rivastigmine (Exelon®, Exelon® Patch)
- Tacrine (Cognex®)
- Anticholinergic drugs, such as:
- Atropine
- Belladonna (Donnatal®, B&O Supprettes®, Bellamine S®)
- Benztropine (Cogentin®)
- Clidinium (Librax®)
- Clozapine (Clozaril®)
- Darifenacin (Enablex®)
- Dicyclomine (Bentyl®)
- Diphenhydramine (Benadryl®, Tylenol PM®)
- Glycopyrrolate (Robinul®)
- Haloperidol (Haldol®)
- Homatropine (Hycodan®)
- Hyoscyamine (Levsin®)
- Ipratropium (Atrovent®)
- Oxybutynin (Ditropan®, Ditropan XL®, Oxytrol®)
- Procyclidine (Kemadrin®)
- Solifenacin (VESIcare®)
- Scopolamine (Transderm Scop®)
- Tiotropium (Spiriva®)
- Tolterodine (Detrol®, Detrol® LA)
- Trihexyphenidyl (Artane®)
- Trospium (Sanctura®, Sanctura® XR)
- Antipsychotic medications
- Pramlintide (Symlin®)
- Tricyclic antidepressants, such as:
- Amitriptyline (Elavil®)
- Amoxapine (Asendin®)
- Clomipramine (Anafranil®)
- Desipramine (Norpramin®)
- Doxepin (Sinequan®, Silenor®)
- Imipramine (Tofranil®, Tofranil PM®)
- Maprotiline (Ludiomil®)
- Nortriptyline (Pamelor®)
- Protriptyline (Vivactil®)
- Trimipramine (Surmontil®).
Written by/reviewed by: Kristi Monson, PharmD; Arthur Schoenstadt, MD
Last reviewed by: Kristi Monson, PharmD