Drug Interactions With Benztropine (Cont.)

Benztropine Interactions Explained

The following sections explain in detail the potentially negative interactions that can occur when benztropine is combined with any of the drugs listed above.
 
Acetylcholinesterase Inhibitor Medications
Taking benztropine with an acetylcholinesterase inhibitor can make both medications less effective. Your healthcare provider may need to monitor you more closely and adjust your dose of these medications to prevent interactions from occurring.
 
Anticholinergic Drugs
Combining an anticholinergic medication with benztropine (which is also an anticholinergic medication) can increase your risk of benztropine side effects, such as dry mouth, constipation, dry eyes, or difficulty passing urine.
 
Antipsychotics
Combining benztropine with antipsychotic medications can increase the risk of certain side effects, such as an intestinal blockage or heat stroke. When using such medications together, make sure to watch for any signs of an intestinal blockage (especially severe constipation) or heat stroke.
 
Pramlintide
Both pramlintide and anticholinergic medications (including benztropine) can slow down the movement of food through the digestive tract. Taking them together can increase the risk of constipation or nausea. Talk with your healthcare provider before combining these medications.
 
Tricyclic Antidepressants
Combining benztropine with a tricyclic antidepressant can increase the risk of certain side effects, such as an intestinal blockage or heat stroke. When using such medications together, make sure to watch for any signs of an intestinal blockage (especially severe constipation) or heat stroke.
 

Final Thoughts on Drug Interactions With Benztropine

It is possible that not all benztropine drug interactions were discussed in this article. Therefore, you should talk with your pharmacist or healthcare provider about any specific drug interactions that may apply to you.
 
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Written by/reviewed by: Kristi Monson, PharmD; Arthur Schoenstadt, MD
Last reviewed by: Kristi Monson, PharmD;