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Drug Interactions With Apomorphine

Apomorphine Interactions Explained

The following sections explain in detail the potentially negative interactions that can occur when apomorphine is combined with any of the drugs listed above.
 
Blood Pressure Medications
Combining apomorphine with high blood pressure medications can increase the risk for dangerously low blood pressure (hypotension). Check with your healthcare provider before taking apomorphine with a blood pressure medicine.
 
Diuretics
Apomorphine can increase the risk of a dangerous irregular heart rhythm (arrhythmia) known as QT prolongation. Some diuretics can cause low potassium or low magnesium levels in the blood, which can further increase the risk of QT prolongation. Check with your healthcare provider before taking apomorphine with a diuretic.
 
Nitrates
Combining apomorphine with a nitrate medication can increase the risk for dangerously low blood pressure (hypotension). Check with your healthcare provider before taking apomorphine with a nitrate.
 
QT-Prolonging Medications
Because apomorphine can increase the risk for QT prolongation, it should be used with caution if you take any other medications that can cause QT prolongation. There may be some situations in which it may be appropriate to use apomorphine with such medications, especially if the heart is closely monitored.
 
5HT3 Antagonists
Apomorphine should never be combined with a 5HT3 antagonist medication, due to the risk of very low blood pressure (hypotension) and loss of consciousness.
 

Final Thoughts on Drug Interactions With Apomorphine

It is possible that not all apomorphine drug interactions were discussed in this article. Therefore, you should talk with your pharmacist or healthcare provider about any specific drug interactions that may apply to you.
 
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